OXTOX but within single-dive limits

[allen]

I have heard rumors that oxymetazoline (Afrin) lowers one's seizure threshold.

[Benderr]

Certain antidepressants are associated with lower seizure thresholds. These include the SSRI (Prozac, Zoloft) and SNRI (Effexor, Cymbalta) class drugs. TCA class antidepressants (Trazodone, Wellbutrin) were once thought to increase seizures, but new research (last year or so) is tending to show that there is no increase in risk of seizures with these drugs at therapeutic doses.

Opioids can increase seizure activity, but really, you shouldn't be in, over, or around water if you're taking those anyway. Some narcolepsy and ADHD drugs lower seizure thresholds, but again, heavy stuff you shouldn't be diving with anyway, and I'd think it wise to stay out of the water if you're narcoleptic. (I suspect many technical divers are close to an ADHD diagnosis anyway)

Some corticosteroids (Prednisone) can increase seizure risk.

All that said, I don't think anyone knows if these drugs contribute to seizures specifically caused by high oxygen exposures. It's easy to think so, but I'm not aware of any studies that have tested this.

[Kelly Jessop]

I have heard rumors that oxymetazoline (Afrin) lowers one's seizure threshold.

Sudafed has been considered a culprit, related to how it effects a brain enzyme.

Gabapentin,which is ironically an antiseizure medicine, and treat neuralgia, has some consideration in lowering OxTox thresholds.

[Kelly Jessop]

I believe too, the diver who died took some medicines I thought

Had not heard that, but know a solo diving accident at Cow some medicine was involved. The accident you mention was never really explained, and has always left me curious.

[MORGAN]

(I suspect many technical divers are close to an ADHD diagnosis anyway)

I suspect that a lot of us combine ADHD and OCD traits. I often think that working as a paramedic and ER nurse made use of my ADHD, and working as an ICU nurse made use of my OCD. Now I'm doing critical care transport which uses both!

[Kelly Jessop]

I suspect that a lot of us combine ADHD and OCD traits. I often think that working as a paramedic and ER nurse made use of my ADHD, and working as an ICU nurse made use of my OCD. Now I'm doing critical care transport which uses both!

There was an article that came out a few years ago that showed people who engage in extreme sports have a decrease in serotonin characteristic.

[Fsworld]

The was an article that came out a few years ago that showed people who engage in extreme sports have a decrease in serotonin characteristic.

Is this the article you are talking about?
http://scienceline.org/2009/07/healt...sk-psychology/

[Kelly Jessop]

Is this the article you are talking about?
http://scienceline.org/2009/07/healt...sk-psychology/

Not the same article,but thank you for sharing. They do mention dopamine,but I recall the article discussed serotonin. I guess we could say that we aren't "adrenlin junkies", but neurotransmitter junkies.

Something I have always been curious about is amygdala development/function of those cave divers in the sport that really push the limits of exploration.

[cerich]

from a chamber experience years ago...being in a REALLY hungover state, the type that you are still drunk sorta but well hung over as well you can tox pretty easy....

[Benderr]

from a chamber experience years ago...being in a REALLY hungover state, the type that you are still drunk sorta but well hung over as well you can tox pretty easy....

So I was ox-toxing all those times in high school?