Originally Posted by http://yarchive.net/space/science/man_in_vacuum.html
The best Earthly comparison is what happens to people who walk into a room containing a pure-nitrogen atmosphere. The analogy is fairly good; to a first approximation, when there's no oxygen present, it doesn't matter whether something else is there or not. Such accidents happen occasionally in industry. (In fact, one happened at the Ariane 5 launch site a few months back.) Sudden loss of consciousness occurs within 10-15s, and death follows quickly. Stringent precautions have to be taken to prevent such accidents, because survival is rare -- you get no warning that you're about to keel over, and rescuers must understand the situation immediately and act very quickly.